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کلرال هیدرات کد 102425 مرک آلمان
102425 Chloral hydrate
suitable for use as excipient EMPROVE® exp Ph Eur,BP,JP,USP
Product information
Grade Ph Eur,BP,JP,USP
Synonyms Trichloroacetaldehyde hydrate
Formula Hill C2H3Cl3O2
Chemical formula Cl3CCH(OH)2
HS Code 2905 59 98
EC number 206-117-5
Molar mass 165.4 g/mol
EC index number 605-014-00-6
CAS number 302-17-0
Chemical and physical data
Solubility 6600 g/l (20 °C)
Melting point 52 °C
Molar mass 165.4 g/mol
Density 1.91 g/cm3 (20 °C)
pH value 3.5 - 5.5 (100 g/l, H2O, 20 °C)
Boiling point 97 °C (1013 hPa) decomposes
Vapor pressure 13 hPa (20 °C)
Safety information according to GHS
Hazard Statement(s) H301: Toxic if swallowed.
H319: Causes serious eye irritation.
H315: Causes skin irritation.
Precautionary Statement(s) P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
Signal Word Danger
Hazard Pictogram(s)
Storage class 6.1B Non combustible substances, toxic
WGK WGK 2 water endangering
Disposal 9
Carcinogenic compounds and flammable compounds labelled "Highly toxic" or "Toxic": container F. Alkyl sulfates are carcinogenic; Take particular care to avoid inhalation and skin contact. To neutralize alkyl sulfates, add dropwise (from a dropping funnel) to concentrated ice-cool Ammonia solution (Cat.No. 105426) with vigorous stirring. Before placing in container D, check the pH with pH Universal indicator strips (Cat.No. 109535).
Safety information
R Phrase R 25-36/38
Toxic if swallowed.Irritating to eyes and skin.
S Phrase S 25-45
Avoid contact with eyes.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Categories of danger toxic, irritant
Hazard Symbol
Toxic
Transport information
Declaration (railroad and road) ADR, RID Kein Gefahrgut
Declaration (transport by sea) IMDG-Code No Dangerous Good
Declaration (transport by air) IATA-DGR UN 3335 AVIATION REGULATED SOLID, N.O.S.(CHLORAL HYDRATE), 9,
Toxicological data
LD 50 oral LD50 rat 479 mg/kg
LD 50 dermal LD50 rat 3030 mg/kg
Specifications
Assay (acidimetric) 99.5 - 101.0 %
Identity passes test
appearance of solution (Ph Eur) passes test
appearance of solution (JP) passes test
Acidic substances passes test
pH-value (10 %; water) 3.5 - 5.5
Chloride (Cl) ≤ 0.007 %
Heavy metals (as Pb) ≤ 0.0020 %
Chloral alcoholate passes test
Non volatile matter ≤ 0.1 %
Benzene passes test
Toluene ≤ 890 ppm
Other residual solvents (Ph.Eur./USP/ICH) excluded by production process
Substances discoloured by H2SO4 passes test
Sulfated ash ≤ 0.10 %
Corresponds to Ph Eur, BP, JP