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Whatman Cyclopore™ membranes are true pore size microporous membranes featuring sharp cut-off and reproducible microfiltration performance characteristics of track etched membranes. The smooth flat membrane ensures particles are retained on the surface so that they are easily visible under a microscope.

Cyclopore membranes are manufactured using proprietary Whatman technology to produce a precision membrane filter with a closely controlled pore size distribution.

Membranes are produced from a pure polymeric film and give exceptional chemical cleanliness. They are free of contaminants, have low tare weight, minimum water adsorption, and very low levels of nonspecific protein binding.

The polycarbonate membranes are hydrophilic and are available in a choice of diameters and pore sizes. The polyester membranes are resistant to most organic solvents, amides, and halogenated hydrocarbons. This broad chemical compatibility makes them suitable for the detection of particles in many corrosive fluids.

Electron micrograph of Cyclopore membrane
with latex beads on surface

• Low affinity for stains providing higher optical contrast and making visibility under a microscope easy
• True surface capture provides easy examination of samples and short analysis times
• Totally transparent membranes available
• Negligible absorption and adsorption of filtrate; nonhygroscopic
• Low tare weights
• No particle shedding provides ultra clean filtrate
• Biologically inert

• Air monitoring
  Trace elements (chemicals, radioactivity) and particulate analysis (dust, pollens, and airborne particles)
• Analytical methods
  Gravimetric analysis, densitometry, emission spectroscopy, x-ray fluorescence, and infrared analysis
• Water analysis
  Absorbable organic halides (AOX), direct count of microorganisms, marine biology and dissolved phosphates, nitrates, and ammonia analysis
• Blood filtration and cell analysis
  RBC deformability, leukocyte removal, RBC filtration and plasmapheresis, chemotaxis, cytology, and cell culture
• General filtration
  Particulate and bacteria removal, cross flow filtration, HPLC sample preparation, and solution filtration
• Microscopy
  Electron microscopy, epifluorescence microscopy, and direct optical microscopy
• Microorganism analysis
  Direct total microbial count, harvesting, concentration, fractionation, yeast, molds, Giardia, Legionella, coliform, and canine microfilaria
• Nucleic acid studies
  Alkaline elution and DNA fragment fractionation
• Oceanographic studies
  Transparent polycarbonate membrane filters provide a new tool for studying planktonic organisms. These ultra thin transparent membranes are strong yet flexible, allowing for planktonic samples to be filtered and the membranes to be mounted directly onto microscope slides. (Ref: Hewes et al. 1998; Graham and Mitchell 1999; Graham 1999.)
• Healthcare
  Biosensors – as a barrier offering controlled diffusion for biological reagents and electrochemical detectors.
  Diagnostic assays – for flow control, sample preparation, blood separation, and capture of latex microparticles.
  Cell biology – for cell culture, chemotaxis, and cytological analyses, e.g., direct staining, isotopic and fluorescence based assays.
  Transdermal drug delivery – as an inert matrix for retention of therapeutics.

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